es-ESen-US
Metabolomics

 

Metabolomics is the last in the chain of the omics sciences, but not the least important, as it is an emerging science. Metabolomics allow us to obtain a metabolic profile of a biological sample (fluids, tissues, cell cultures, etc.), in order to discover a set of metabolites and / or biomarkers depending on the aims and the nature of the data; additionally, it allows inferences of cellular mechanisms at the molecular level.

We provide a personalized data analysis service using bioinformatics and statistical techniques for different biological groups (microorganisms, animals, plants and humans), carrying out analyses, whether directed or not directed.

Metabolomics has several applications, including:

  • Clinical Research: Identify and validate biomarkers correlated with disease states
  • Pharmaceutical / Cosmetic: Identify and discover metabolites
  • Agriculture: Identify and know the metabolic pathways for optimizing crop development, performance improvement and resistance to pesticides / herbicides.
  • Environmental: Identify metabolites related to the effects of chemical substances and other types of stress from biological or non-biological sources.

The establishment of a metabolic profile or Fingerprint gives us information on the biologically active compounds present in a sample. It is carried out for mass spectrometry, an essential analytical technology in metabolomics and lipidomics studies.

We have established a bioinformatics workflow that allows us to search for correlations between the mass spectra obtained and the MS / MS spectra library and databases to perform a finer identification of the metabolites, carrying out quantitative and qualitative analyses. These results are critically analysed by our researchers who will establish the relevant and promising metabolites found in the study.

Further, we can provide guidance on the experimental approach, including assistance in experimental design depending on the achievable objectives, adequate statistical sampling, number of samples to be processed, and logistical aspects, among others.